Interleukin-1 Receptor Antagonist Protein (IRAP): Interleukin-1 (IL-1) is a cytokine that is secreted by many types of cells and plays an important role in inflammation. In the joint it accelerates the deterioration of tissues such as joint cartilage. IRAP blocks IL-1 from binding to tissues and inhibits the damaging consequences of IL-1.
Your veterinarian will collect blood into a specially prepared syringe containing glass beads that stimulate production of IRAP. This syringe is then incubated overnight and centrifuged to separate the plasma (abundant with IRAP) from the blood cells. The sample is separated into individual vials and frozen for future use. Your veterinarian will recommend a treatment protocol.
PRP utilizes technology similar to that developed for IRAP. PRP contains increased levels of many different beneficial growth factors. Like IRAP, your veterinarian will collect blood from your horse into a special syringe which is then centrifuged. However, the resultant plasma is available for injection the same day. This plasma can then be injected into a variety of acute and chronic tendon or ligament conditions. Applications include superficial and deep flexor tendonitis, suspensory desmitis, collateral ligament injuries and muscle injuries. ACP and PRP are both exciting technologies that can be incorporated into your horse’s current recovery and rehabilitation regime.